i>Manjusri, a Chinese Buddhist painting in the collection of the Osaka Fine Arts Merchants’ Association, is an important testimony to the cultural exchange between China and Japan, and holds significant historical and artistic value. Over time, the painting had suffered from a variety of deterioration, including extensive fading, tears, creases and adhesive stains. In order to select the most appropriate restoration and mounting approach, this study conducted scientific analyses. The paper samples were tested and analyzed to understand the physical properties and degradation state of the paper. Based on these findings, restoration materials were selected, and a detailed treatment and mounting plan was formulated. This restoration object was a typical Chinese painting with Japanese mounting. During the restoration and remounting process, the principle of minimal intervention was followed to preserve the authenticity and integrity of the artwork. In the treatment process, the combination of modern analytical methods and traditional restoration and mounting techniques, enabled accurate evaluation of the paper condition, and thus provided a sound scientific basis for restoration decisions, effectively slowing paper deterioration, and maximizing the visual and structural restoration of the artwork. This study could provide a practical reference and theoretical support for the conservation and restoration of similar paper cultural relics.