Tomb murals are an important part of cultural heritage in China. It is very urgent and necessary to record the color information of murals accurately and effectively by digital measures in the first place before the intervention of a tomb site. However, due to the deviation of the output frequency (color) of the light source and the characteristics of the photosensitive elements (CCD camera, etc.) used in the image acquisition system, the problem of high-fidelity reproduction of image colors has always been a key factor restricting the establishment of accurate digital archives of tomb murals. With the aim of solving this problem, the Western Han mural tomb at Xi’an Jiaotong University was used as an example to discuss the difficulties and key technologies in the process of color correction of the mural images collected from the fully enclosed tomb murals under a single light source. In view of the low accuracy of color correction of mural images caused by the limited collection conditions of tomb murals and the low quality of collected images, a complete color correction solution based on the 3D-look-up table algorithm is proposed. The trials show that the method improved the accuracy of color correction. This study duplicated the original features of murals with a high-resolution and high-fidelity result, which makes sense to the conservation, sharing, research and utilization of tomb murals and other cultural heritage objects.