While traditional techniques are still used for the restoration of calligraphy and painting works, modern analytical technologies can also be included to achieve cultural relic restoration effects by following the relevant principles. This paper takes the restoration of a calligraphy work by Yang Jisheng in the collection of Fengxian Museum as a case to show how the combination of modern analytical technologies and traditional restoration techniques—by selecting suitable materials for restoration and conservation through the analysis of disease types, paper materials and mounting characteristics of the work—can achieve the best restoration effect.