Acrylic polymers have been widely used in the consolidation, bonding and sealing of cultural relics because of their various properties, such as film formation, high reversibility and hydrophobicity. Typical acrylic polymers (e.g. Paraloid B-72 and Primal AC-33) have a long history and a wide range of application in the conservation of cultural relics. However, considering the various materials and preservation conditions of different cultural relics, it is impossible to meet all the conservation requirements using only these popular materials. This paper reviews the application of other atypical acrylic polymers, including Paraloid B-44, B-48N, B-66, B-67, Primal SF-016, B-60A, MC-76, WS-24, and other emulsion acrylic polymers, to the conservation of cultural relics. The major chemical components, properties, advantages and disadvantages of the aforementioned materials are compared with regard to their different performances, the objects they are applied to, and methods and effects of these materials. By summarizing the history and current developmental trends, more alternates for the selection of acrylate materials for conservators in the future could be provided.