Conservation and restoration of cultural relics often produce gaseous and dust pollutants which do harm to human health and pose hazards to the safety of heritage objects. A professional, scientific and applicable ventilation system is the best measure for pollution control. Because of their specificity and complexity, the ventilation requirements of conservation facilities are totally different from those typically encountered by civil engineers. Thus problems often occur in museum constructional engineering due to the lack of relevant experience. In this paper, technology and design ideas and key parameters of ventilation systems for conservation facilities are discussed based on the standards of laboratory and experience of relevant projects. It could be helpful to other museum construction projects.