In July 2011, a huge coagulation was excavated from the Nan’ao Ⅰ shipwreck archaeological site. It was made up of stones, porcelains and iron, copper and wooden cultural objects. We carried out analyses, surface cleaning, overall circulating spray desalination, microbial control, local strengthening and exhibition stand manufacturing, etc., and then achieved overall conservation and exhibition of the coagulation. This study provides a successful reference case for the overall conservation of coagulations excavated from ocean.