Considering acidification of literature paper and the drawbacks of traditional deacidification methods, we developed a set of automated literature deacidification technologies to automatically process the procedures. The process includes controlled automatic spraying and automatic page-turning. The process is an ideal conservation method and a good deacidification method. The deacidification process was strictly controlled in order to achieve ideal effects. The optimum parameters for books having a pH below 5 were set as follows:1) the mass concentration of nano-particulate magnesium oxide was 5%; 2) the pump output flow rate was 10 mL/min and; 3) the air pressure was 0.16 Mpa. The paper properties, residual alkalinity, waterproof characters and particle distribution on the paper after deacidification treatment were tested to evaluate the deacidification method. The results show that the automated deacidification method we developed is safe and effective.