At present, there is a lack of specialized research on Jin-hua-yin silver ingots. In our study, in order to enrich the research in this regard, we analyzed nondestructively the elemental composition of six silver ingots with three Chinese characters “Jin Hua Yin” and six ordinary silver ingots of the Ming Dynasty, using X-ray fluorescence spectrometry (XRF). The results show that the silver content of the Jin-hua-yin silver ingots is higher and that the gold content is significantly higher than the ordinary silver ingots. The elements of iron, lead, copper and gold were measured on the surface of each side. The surface may contain corrosion products in a powdery form, and some of the Jin-hua-yin silver ingots have tightly-bound mercury elements on the surface. The silver contents of the ordinary ingots have individual differences, and their gold contents are all lower than those of the Jin-hua-yin silver ingots. In addition, the Jin-hua-yin silver ingots are similar in shape to the ordinary silver ingots of the same period. The analysis results provide a scientific basis for understanding the compositions and production methods of Jin-hua-yin silver ingots in the Ming Dynasty.