Considering the huge quantity, poor storage conditions and severe acidification of neoteric and modern paper literature in China, we sought to optimize the existing deacidification technologies of Nanjing Museum, and to integrate aquatic solution deacidification, microwave drying and freeze-drying technologies massively. At least 30 books were deacidified in each batch. After deacidification, the pH values and alkaline reserves were both improved and the paper shrinkage rate was controllable. A preliminary system that incorporates both the technology and demonstration of it for massive deacidification has been created in order to provide technical support for the conservation of the huge amount of neoteric and modern paper literature.